Related Experiment Video
Updated: Aug 28, 2025

The Soft Agar Colony Formation Assay
Published on: October 27, 2014
BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation
Mengdan Yu1,2, Qianwei Zhao1, Jinxia Li2
1Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450052, China.
Abstract:
Lung cancer is one of the most prevalent and malignant cancers, among which lung adenocarcinoma (LUAD) accounts for the majority and remains a major cause of cancer-related mortality worldwide (Cui et al., 2019). Despite the growing intensity of research on the pathobiology and progression of lung cancer and the fact that many genes have been identified as potential drivers and targets for therapy (Luo et al., 2019; Zhang et al., 2019), the treatment and prognosis of lung cancer patients have hardly improved. Therefore, this study aimed to investigate the precise mechanism of lung cancer development and explore efficient diagnostic and therapeutic methods for clinical treatment.
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