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Updated: Aug 28, 2025
Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae
Published on: April 30, 2018
Cell type markers indicate distinct contributions of decidual stromal cells and natural killer cells in preeclampsia
Kalle T Rytkönen1,2, Nigatu Adossa1, Mehrad Mahmoudian1,2
1Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.
In Brief:
Preeclampsia is a common serious disorder that can occur during pregnancy. This study uses integrative analysis of preeclampsia transcriptomes and single-cell transcriptomes to predict cell type-specific contributions to preeclampsia.
Abstract:
Preeclampsia is a devastating pregnancy disorder and a major cause of maternal and perinatal mortality. By combining previous transcriptomic results on preeclampsia with single-cell sequencing data, we here predict distinct and partly unanticipated contributions of decidual stromal cells and uterine natural killer cells in early- and late-onset preeclampsia.
