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Area of Science:

  • Gastroenterology
  • Clinical Diagnostics
  • Health Services Research

Background:

  • Validated questionnaires are crucial for minimizing diagnostic bias and standardizing symptom assessment in clinical studies.
  • European guidelines recommend the adult (aCPQ) and pediatric (pCPQ) carbohydrate perception questionnaires for diagnosing carbohydrate intolerances.
  • The clinical implementation of these guidelines necessitates the availability of validated translations.

Purpose of the Study:

  • To develop and implement a standardized translation process for the adult and pediatric carbohydrate perception questionnaires (aCPQ and pCPQ).
  • To increase the accessibility of validated diagnostic tools for carbohydrate intolerances across Europe.

Main Methods:

  • A structured, 5-phase workflow (foundation, nomination, translation, revision, cognitive debriefing) was developed based on Rome foundation recommendations.
  • Clinical experts participated in the translation process to ensure linguistic and cultural adaptation.
  • The process was centrally organized for efficiency and consistency.

Main Results:

  • The aCPQ was translated into eight languages (Bulgarian, French, Hungarian, Italian, Polish, Romanian, Russian, Slovenian) within eight months.
  • The pCPQ was translated into three languages (Dutch, French, Romanian).
  • The potential reach of the aCPQ increased from 160 million to over 500 million Europeans; the pCPQ's reach expanded from 92 million to 193 million Europeans.

Conclusions:

  • A centrally organized, structured translation process for validated questionnaires was successfully developed and implemented.
  • This standardized procedure facilitates the harmonization of translated diagnostic tools.
  • The availability of these translated questionnaires supports broader clinical application and research comparability in diagnosing carbohydrate intolerances.