Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Structure01:45

Kidney Structure

70.4K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
70.4K
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

50
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
50
Drug Elimination by Renal Route: Tubular Reabsorption01:22

Drug Elimination by Renal Route: Tubular Reabsorption

3.6K
During the process of renal excretion, as the glomerular filtrate progresses to the distal convoluted tubule (DCT), drugs that are highly permeable, lipophilic, and nonionized undergo passive reabsorption from the tubular fluid into the surrounding peritubular capillaries. This reabsorption process restricts their elimination through the kidneys. However, the majority of drugs are either weak acids or weak bases, and their ionization level is dependent on pH. By altering the pH of urine, the...
3.6K
Blood and Nerve Supply to the Kidney01:18

Blood and Nerve Supply to the Kidney

1.6K
The kidneys are vital organs responsible for filtering and cleaning blood, removing waste products, and regulating electrolyte levels. To perform these essential functions, they require a constant and robust blood supply.
Bloody Supply to the Kidneys:
The kidneys receive their blood supply from the renal arteries, which branch off from the abdominal aorta—the main artery supplying the abdomen and lower body. The renal arteries enter the kidneys at the hilum, a notch on the medial side of...
1.6K
Drug Elimination by Renal Route: Glomerular Filtration01:17

Drug Elimination by Renal Route: Glomerular Filtration

5.8K
The kidney serves as the primary organ responsible for eliminating drugs and their metabolites from the body. This process, known as renal elimination, starts with glomerular filtration and results in urine formation. Each kidney houses millions of functional units called nephrons, where urine production takes place. A nephron has two main components: a renal corpuscle and a renal tubule. Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent...
5.8K
Renal Drug Excretion: Tubular Secretion01:28

Renal Drug Excretion: Tubular Secretion

266
Active tubular secretion is a robust, energy-demanding process that utilizes carrier systems to transport drugs into renal tubules. The active renal secretion systems include the organic anion transporter (OAT) for weak acids and the organic cation transporter (OCT) for weak bases. Structurally similar drugs can compete for the same transporter, potentially leading to drug accumulation and toxicity. However, this principle can be exploited therapeutically. One example is probenecid (Probalan),...
266

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oxygen-Independent Supramolecular Nanoplatform for Photothermal-Thermodynamic Therapy against Periodontal Anaerobic Infections.

Advanced healthcare materials·2026
Same author

Immunosuppressive regimens and long-term kidney transplant outcomes: A dual survival modeling framework.

PloS one·2026
Same author

Acthar Gel treatment in patients with rheumatoid arthritis, systemic lupus erythematosus, or dermatomyositis/polymyositis: analysis of physician-reported charts.

Journal of comparative effectiveness research·2026
Same author

Does Voclosporin Redefine Lupus Nephritis Treatment? A Tri-Focal View of Efficacy, Safety, and Costs.

Current medical science·2026
Same author

Kidney Transplantation for Lithium Nephrotoxicity is Associated With Noninferior Graft and Patient Survival: A National Donor-Stratified Registry Analysis.

Clinical transplantation·2026
Same author

H<sub>2</sub>S-Amplified "Three-in-One" Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene-Embedded COF/MOF Hybrid.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same journal

Malnutrition trends in displaced Rohingya children from 2017 to 2024: a comprehensive 7-year repeated cross-sectional analysis.

BMJ global health·2026
Same journal

Changes in the use of basic obstetric care in sub-Saharan Africa: evidence from demographic and health surveys using an Oaxaca-Blinder approach.

BMJ global health·2026
Same journal

Identifying delays to emergency laparotomy in a low-resource setting using the Three Delays Model: a prospective observational study (DEL study).

BMJ global health·2026
Same journal

Antibiotic dispensing practices and determinants among informal healthcare providers in low- and middle-income countries: a mixed-methods scoping review.

BMJ global health·2026
Same journal

Risk perceptions of high-dose primaquine and tafenoquine among <i>Plasmodium vivax</i> malaria stakeholders in Ethiopia: a qualitative study.

BMJ global health·2026
Same journal

Sexual and reproductive health needs of refugee women on Lesbos, Greece: a participatory cross-sectional study.

BMJ global health·2026
See all related articles

Related Experiment Video

Updated: Aug 28, 2025

Reliable and High Efficiency Extraction of Kidney Immune Cells
09:15

Reliable and High Efficiency Extraction of Kidney Immune Cells

Published on: August 19, 2016

10.5K

Identifying kidney trade networks using web scraping data.

Meng-Hao Li1, Abu Bakkar Siddique1, Brian Wilson1

  • 1Schar School of Policy and Government, George Mason University, Arlington, Virginia, USA.

BMJ Global Health
|September 16, 2022
PubMed
Summary
This summary is machine-generated.

This study used online newspaper scraping and machine learning to analyze transnational kidney trade networks. This approach effectively compiles data on illegal organ trafficking, addressing a critical gap in empirical research.

Keywords:
Control strategiesHealth policy

More Related Videos

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology
09:00

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology

Published on: March 27, 2018

7.5K
An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
10:14

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney

Published on: November 1, 2018

13.8K

Related Experiment Videos

Last Updated: Aug 28, 2025

Reliable and High Efficiency Extraction of Kidney Immune Cells
09:15

Reliable and High Efficiency Extraction of Kidney Immune Cells

Published on: August 19, 2016

10.5K
Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology
09:00

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology

Published on: March 27, 2018

7.5K
An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
10:14

An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney

Published on: November 1, 2018

13.8K

Area of Science:

  • Transplant Ethics
  • Public Health
  • Criminology

Background:

  • Illegal kidney trade is increasing globally, with emerging regional hubs facilitating exploitation.
  • Existing law enforcement efforts are challenged by complex, transnational networks bypassing domestic regulations.
  • A lack of systematic data collection hinders understanding of kidney trade patterns.

Purpose of the Study:

  • To systematically collect data on transnational kidney trade networks.
  • To develop and apply machine learning for identifying relevant news articles on kidney trade.
  • To build country-level networks of kidney trade based on news reports.

Main Methods:

  • Online newspaper scraping of 10,419 English articles from South Asian newspapers (Jan 2016-May 2019).
  • Text mining to extract keywords and machine learning algorithms for article classification.
  • Network analysis to map country-level kidney trade.

Main Results:

  • Online newspaper scraping and machine learning provide a viable method for data compilation.
  • The study successfully identified and analyzed transnational kidney trade networks from news data.
  • This approach offers a promising solution for data collection in the absence of empirical data.

Conclusions:

  • Machine learning and web scraping are effective tools for studying illegal organ trafficking.
  • Systematic data collection is crucial for understanding and combating kidney trade networks.
  • The methodology presented can be applied globally to address the shortage of empirical data on organ trafficking.