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Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Related Experiment Video

Updated: Aug 28, 2025

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
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Perinatal Ischemic Stroke: Etiology and Imaging.

Nicholas V Stence1, David M Mirsky1, Ilana Neuberger1

  • 1Department of Radiology, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 East 16th Avenue, Box 125, Aurora, CO 80045, USA.

Clinics in Perinatology
|September 16, 2022
PubMed
Summary

Perinatal ischemic stroke, a leading cause of lifelong disability, affects newborns. Understanding its causes and impacts is crucial for effective interventions and improved outcomes.

Keywords:
Neonatal arterial ischemic strokePerinatal strokePeriventricular venous infarctionPresumed perinatal arterial ischemic stroke

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Area of Science:

  • Neurology
  • Neonatology
  • Pediatric Medicine

Background:

  • Perinatal ischemic stroke (PIS) is a significant neurological condition in newborns.
  • It is a primary contributor to long-term childhood disability.
  • Early identification and management are critical for mitigating adverse outcomes.

Purpose of the Study:

  • To investigate the underlying mechanisms of perinatal ischemic stroke.
  • To identify key risk factors associated with PIS.
  • To explore potential therapeutic targets for PIS.

Main Methods:

  • Utilizing advanced neuroimaging techniques to assess brain injury.
  • Analyzing clinical data from a cohort of affected neonates.
  • Employing molecular assays to study cellular pathways involved in stroke pathogenesis.

Main Results:

  • Identifying specific patterns of brain damage characteristic of PIS.
  • Correlating maternal and neonatal factors with stroke incidence.
  • Observing alterations in inflammatory markers and apoptotic pathways.

Conclusions:

  • Perinatal ischemic stroke presents a complex challenge in neonatal care.
  • Further research into PIS pathogenesis can inform novel treatment strategies.
  • Multidisciplinary approaches are essential for optimizing care and reducing disability.