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Cuprizone-induced Demyelination in Mouse Brain is not due to Depletion of Copper
Megan L Morgan1, Wulin Teo1, Yda Hernandez1
1Cumming School of Medicine, Department of Clinical Neurosciences, University of Calgary, Hotchkiss Brain Institute, Calgary, 3330 Hospital Drive N.W. HRIC 1B37A, Calgary, AB, T2N 4N1, Canada.
ASN Neuro
|September 17, 2022
Abstract
Summary Statement:
The demyelinating effects of CPZ are not due to Cu deficiency but are instead consistent with acute toxicity of a CPZ + Cu complex.
