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SARS-CoV-2 Seroprevalence Among First Responders in Northeastern Ohio, 2020
Xiaochun Zhang1,2, Elie Saade3,2, Jaime H Noguez1,2
1Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Public Health Reports (Washington, D.C. : 1974)
|September 17, 2022
Summary
First responders had a 2.4% SARS-CoV-2 seroprevalence, with most infections being asymptomatic. Despite high occupational exposure, infection control measures appeared effective in preventing widespread work-related COVID-19 transmission.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- First responders face elevated COVID-19 infection risks due to frontline roles.
- Assessing SARS-CoV-2 seroprevalence is crucial for understanding transmission dynamics in this high-risk group.
Purpose of the Study:
- To determine the seroprevalence of SARS-CoV-2 infection among first responders in northeastern Ohio.
- To identify factors associated with seropositivity in this occupational group.
Main Methods:
- A cross-sectional study involving 3080 first responders from May to September 2020.
- Utilized surveys for demographic data and infection history, alongside SARS-CoV-2 immunoglobulin G antibody testing.
Main Results:
- Overall seroprevalence was 2.4% (73/3080), with 46.6% of seropositive cases being asymptomatic.
- Seropositivity rates varied by occupation, highest in administration/support staff (3.8%) and lowest in law enforcement (0.8%).
- Black participants showed higher seroprevalence than other racial groups, despite reporting lower exposure.
Conclusions:
- First responders exhibited seroprevalence rates comparable to administrative staff, suggesting effective infection control.
- High work-associated exposure did not directly correlate with higher seroprevalence, reinforcing the efficacy of implemented safety protocols.
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