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Related Experiment Videos

Local autonomic failure affecting a limb.

R H Johnson, B J Robinson

    Journal of Neurology, Neurosurgery, and Psychiatry
    |June 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Localized autonomic failure can cause limb sweating loss and temperature changes. This condition, likely due to spinal cord lesions, affects autonomic functions like sweating and vasomotor control in a single limb.

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    Area of Science:

    • Neurology
    • Autonomic Neuroscience

    Background:

    • Autonomic failure typically presents with widespread symptoms.
    • Localized autonomic dysfunction is less commonly reported.

    Observation:

    • Three patients exhibited isolated autonomic failure in one limb, with significant sweating loss.
    • Physiological studies indicated preganglionic autonomic lesions, not sweat gland issues.
    • Vasomotor control was also impaired in the affected limb.

    Findings:

    • The autonomic failure appeared localized, with no generalized deficits or neurological abnormalities.
    • In two cases, the condition was lifelong and static; in the third, it preceded sensory loss.
    • Evidence suggests discrete spinal cord lesions as the probable cause.

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    Implications:

    • Isolated autonomic failure can manifest as limb-specific sweating and temperature dysregulation.
    • This highlights the possibility of focal cord lesions causing localized autonomic symptoms.
    • Further research into localized autonomic disorders is warranted.