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Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology

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Published on: July 21, 2018

Mucosa-interfacing electronics.

Kewang Nan^1,2, Vivian R Feig^2,3, Binbin Ying^1,2

¹Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA USA.

Nature Reviews. Materials

|September 20, 2022

Summary

This summary is machine-generated.

Mucosa-interfacing electronics offer promising biosensing potential but face challenges. This review compares skin and mucosal electronics, outlining design considerations for future personalized mucosa biosensing systems.

Keywords:

Biomedical engineering Sensors and biosensors

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Area of Science:

Bio-integrated electronics
Biomedical engineering
Sensor technology

Background:

The body's mucosal surfaces are rich in biometric signals, ideal for long-term biosensing.
Current mucosa-interfacing electronics face hurdles in interface stability, device management, and power/data transmission.
Skin-interfacing electronics have advanced significantly, offering continuous, untethered monitoring.

Purpose of the Study:

To bridge the gap between skin and mucosa-interfacing electronics.
To compare the properties and functions of skin and mucosal surfaces for biosensing.
To outline design considerations for next-generation mucosa-interfacing electronics.

Main Methods:

Review of current literature on skin and mucosa-interfacing electronics.
Comparison of physiological signals accessible via skin and mucosal surfaces.
Survey of state-of-the-art developments in bio-integrated electronics.

Main Results:

Mucosal surfaces present unique challenges and opportunities for biosensing compared to skin.
Key physiological signals accessible through mucosa-lined organs are identified.
Design considerations for robust and effective mucosa-interfacing electronic systems are proposed.

Conclusions:

Developing advanced mucosa-interfacing electronics is crucial for personalized biosensing.
Overcoming current challenges will unlock significant scientific and clinical potential.
This review provides a foundation for future innovations in internal organ biosensing.