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Updated: Aug 28, 2025

Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery
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Tunable Toxicity of Bufadienolides is Regulated through a Configuration Inversion Catalyzed by a Short-Chain

Ge Ye1, Weihuan Huang2, Zeping Chen1

  • 1Institute of Traditional Chinese Medicine and Natural Products, International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, College of Pharmacy, Jinan University, 855 Xingye East Avenue, 510632, Guangzhou, P. R. China.

Chembiochem : a European Journal of Chemical Biology
|September 20, 2022
PubMed

Keywords:
3-epi bufadienolideshydroxysteroid epimerizationshort-chain dehydrogenase/reductasetoad livertoxicity

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