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Related Experiment Video

Updated: Aug 28, 2025

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer
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Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer

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An open-source bioink database for microextrusion 3D printing.

Bhushan Mahadik1,2, Ryan Margolis1, Shannon McLoughlin1,2

  • 1Fischell Department of Bioengineering, University of Maryland, College Park, MD, United States of America.

Biofabrication
|September 20, 2022
PubMed
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This summary is machine-generated.

A new open-source bioink database aids 3D bioprinting research by cataloging formulations and printing parameters. This tool helps scientists explore biomaterials and cell printing conditions for tissue engineering advancements.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • 3D bioprinting is crucial for fabricating complex engineered tissues in regenerative medicine.
  • Increasing bioink complexity and printing conditions challenge the replication and innovation of bioprinting strategies.
  • A centralized, searchable database is needed for 3D printing formulations and parameters.

Purpose of the Study:

  • To develop the first open-source bioink database for extrusion-based 3D printing.
  • To provide a searchable platform for biomaterials and cells used in 3D printing.
  • To facilitate community-driven database growth through an open-source portal.

Main Methods:

  • Developed a publicly available bioink database for extrusion-based 3D printing.
Keywords:
3D printingbioinkdatabaseextrusionopen-source

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  • Implemented an open-source portal for researchers to contribute publication data.
  • Analyzed printability domains of poly(ϵ-caprolactone) and gelatin methacrylate using the database.

    • Main Results:

    • The database enables rapid searching of biomaterials and cells for 3D printing.
    • Identified printability domains, including successful and unsuccessful printing conditions (pressure, temperature, speed).
    • Correlated printing parameters (needle size, type) with cell-based 3D printing compatibility.

    Conclusions:

    • The bioink database is a valuable tool for the 3D printing and bioprinting community.
    • Facilitates research advancement and aids in the standardization of bioprinting techniques.
    • Supports rapid identification of optimal printing parameters for various biomaterials and cell types.