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Updated: Aug 28, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
Published on: May 15, 2019
[National Competence Network Contergan - Ensuring medical care for people with thalidomide embryopathy]
Rudolf Beyer1, Klaus M Peters2, Jan Schulte-Hillen3
1Abteilung für Anästhesiologie, Intensiv- und Schmerzmedizin, Schön-Klinik, Hamburg.
Abstract:
In 2021, a national network of multidisciplinary medical competence-centers has established itself in Germany that is committed to ensuring the care of people with thalidomide embryopathy. This article would like to draw attention to this competence network and give an overview of the most important medical care needs of aging people with thalidomide-induced body and sensory impairments. Here, the available scientific evidence and clinical peculiarities in medical care from a general medical-internal, orthopedic-paintherapeutic, sociomedical and psychosomatic-psychotherapeutic perspective will be presented and necessary tasks for the future will be discussed.
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