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Updated: Aug 28, 2025

Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates
Published on: June 17, 2016
Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation
Khorshid Kamguyan1, Saeed Zajforoushan Moghaddam1, Abolfazl Nazbar2
1Department of Chemistry, Technical University of Denmark 2800 Kgs. Lyngby Denmark esth@kemi.dtu.dk.
Abstract:
Cell-imprinted substrates direct stem cell differentiation into various lineages, suggesting the idea of lineage-specific nanotopography. We herein examined the surface topography of five different imprinted cell patterns using AFM imaging and statistical analysis of amplitude, spatial, and hybrid roughness parameters. The results suggest that different cell imprints possess distinguished nanotopographical features.
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