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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Next-generation Sequencing03:00

Next-generation Sequencing

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The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
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An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
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Three Grand Challenges in High Throughput Omics Technologies.

Prashanth Suravajhala1,2, Alexey Goltsov3

  • 1Amrita School of Biotechnology, Amrita Vishwavidyapeetham, Amritapuri, Clappana, Kerala 690525, India.

Biomolecules
|September 23, 2022
PubMed
Summary
This summary is machine-generated.

Next-generation sequencing (NGS) and bioinformatics enable genomic assays in clinical practice. These advancements improve disease diagnosis and treatment strategies.

Area of Science:

  • Genomics
  • Bioinformatics
  • Translational Medicine

Background:

  • Genomic assays have evolved significantly over time.
  • Next-generation sequencing (NGS) and bioinformatics are key drivers of this evolution.

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  • The integration of genomic data into clinical practice is a major goal.