[Radiosensitizing effect of hyperthermia on normal and tumor tissues]

Proceeding from an analysis of experimental and clinical data the authors have considered some peculiarities of the radiosensitizing effect of hyperthermia on normal and tumor tissues in different temperature exposure regimens of heating and various schemes of heating combined with irradiation. Possible importance of induced thermal tolerance in the effects of thermal radiation exposure was assessed. The analysis of studied correlations has shown that maximum development of thermal tolerance of the human skin can be induced by heating up to 41-42 degrees C and temperature inducing this effect for human tumors can be lower.