Related Experiment Video
Updated: Aug 27, 2025

Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
Published on: January 29, 2014
Severe hemolysis with negative direct antiglobulin test: A case report
Mahin Behzadifard1, Ali Arianezhad1, Ali Bandehzadeh1
1Dezful University of Medical Sciences, Dezful, Iran.
This case study highlights a severe hemolytic anemia case in a type 2 diabetes mellitus patient. Treatment with corticosteroids and rituximab, alongside transfusions, proved effective in stabilizing the patient.
Area of Science:
- Hematology
- Internal Medicine
- Endocrinology
Background:
- A 49-year-old woman with type 2 diabetes mellitus (T2DM) presented with severe anemia and symptoms suggestive of hemolysis.
- Initial investigations revealed significant anemia (Hb 4.8 g/dL), elevated bilirubin, and lactate dehydrogenase (LDH), indicating hemolysis.
More Related Videos
10:27Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
11:28Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques
Published on: March 13, 2015
Related Concept Videos
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Rh Blood Group
Blood Typing
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
The ABO Blood Group
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...