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Therapeutic plasma exchange as adjunct therapy for bullous pemphigoid
Deep Phachu1, Ibrahim Elali1, Barbara Garay1
1Division of Nephrology, University of Connecticut, Farmington, Connecticut, USA.
Abstract:
Bullous pemphigoid (BP) is a rare autoimmune blistering disease caused by pathogenic antibodies which deposit into the dermo-epidermal junction. We present a case of bullous pemphigoid in a young female refractory to initial therapy with immunosuppressives and steroids who experienced significant improvement in blister burden after a course of adjunct therapeutic plasma exchange (TPE). This case report provides valuable insight into the benefit of utilizing TPE for BP and provides treatment specifics regarding use of TPE in a patient with BP.
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