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Updated: May 19, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Pregnancy in Patients With Renal Transplant
Ibrahim Elali1, Corrine K Nelson1, Linda M Szymanski1
1Division of Nephrology, Hypertension, and Transplantation, Department of Medicine, UCLA David Geffen School of Medicine, Harbor-UCLA Medical Center, and the Lundquist Institute, Torrance, California; and the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, the Division of Nephrology and Hypertension, Department of Medicine, and the Department of Pharmacy, Mayo Clinic, Rochester, Minnesota.
Abstract:
Pregnancy after kidney transplantation is increasingly common. Maternal and fetal outcomes are generally favorable with stable allograft function and individualized care. Current guidelines recommend waiting at least 1 year posttransplant before attempting pregnancy to ensure graft stability and reduce the risk of complications. Prepregnancy counseling is essential and should include information about transitioning to a compatible immunosuppressive regimen to minimize teratogenic risks. Pregnancy management in transplant recipients requires a multidisciplinary approach involving the transplant clinician, transplant pharmacist, and maternal-fetal medicine specialist. This review highlights key considerations and clinical recommendations across each phase of pregnancy care: prepregnancy planning, pregnancy management, and postnatal follow-up, emphasizing the importance of collaborative, patient-centered strategies for reproductive health in kidney transplant recipients.
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Renal Failure: Dose Adjustments
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...

