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A Hospital-based Managed Alcohol Program in a Canadian Setting
Seonaid Nolan1, Christopher Fairgrieve, Huiru Dong
1From the British Columbia Centre on Substance Use, Vancouver, BC, Canada (SN, HD); Department of Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada (SN); Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada (CF); School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada (HD); Providence Health Care, St. Paul's Hospital, Vancouver, BC, Canada (EG, HvH, BPP); Department of Family Medicine, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada (MM); Section of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Harborview Medicine Center, Seattle, WA (JIT); and Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston Medical Center, Boston, MA (JHS).
Objectives:
A managed alcohol program (MAP) is a harm reduction strategy that provides regularly, witnessed alcohol to individuals with a severe alcohol use disorder. Although community MAPs have positive outcomes, applicability to hospital settings is unknown. This study describes a hospital-based MAP, characterizes its participants, and evaluates outcomes.
Methods:
A retrospective chart review of MAP participants was conducted at an academic hospital in Vancouver, Canada, between July 2016 and October 2017. Data included demographics, alcohol/substance use, alcohol withdrawal risk, and MAP indication. Outcomes after MAP initiation included the change in mean daily alcohol consumption and liver enzymes.
Results:
Seventeen patients participated in 26 hospital admissions: 76% male, mean age of 54 years, daily consumption prehospitalization of a mean 14 alcohol standard drinks, 59% reported previous nonbeverage alcohol consumption, and 41% participated in a community MAP. Most participants were high risk for severe, complicated alcohol withdrawal and presented in moderate withdrawal. Continuation of community MAP was the most common indication for hospital-based MAP initiation (38%), followed by a history of leaving hospital against medical advice (35%) and hospital illicit alcohol use (15%). Hospital-based MAP resulted in a mean of 5 fewer alcohol standard drinks daily compared with preadmission ( P = 0.002; 95% confidence interval, 2-8) and improvement in liver enzymes, with few adverse events.
Conclusions:
Participation in a hospital-based MAP may be an effective safe approach to reduce harms for some individuals with severe alcohol use disorder. Further study is needed to understand who benefits most from hospital-MAP and potential benefits/harms following hospital discharge.
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