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[Pleomorphic liposarcoma arising in an unusual site. A case report]
Gloria Meijide Santos1, María Poch Arenas1, Carlos Javier Grau Polo1
1Servicio de Anatomía Patológica, Hospital Universitario de Cabueñes, Gijón, España.
Summary
This study details a rare case of pleomorphic liposarcoma in the small intestine of a 75-year-old man. The findings highlight the importance of considering unusual tumor locations in differential diagnoses for gastrointestinal neoplasms.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Liposarcomas are common malignant mesenchymal neoplasms, typically found in extremities and retroperitoneum.
- Intestinal liposarcomas are exceedingly rare, with most reported cases involving well-differentiated or undifferentiated subtypes.
Observation:
- A 75-year-old male presented with severe anemia, leading to the discovery of a 5cm jejunal loop thickening via CT scan.
- Surgical resection revealed a 12x6cm ulcerated, polypoid mass.
- Microscopic examination identified a well-circumscribed, ulcerated tumor composed of pleomorphic lipoblasts within a sarcomatous stroma.
Findings:
- The case represents a rare instance of pleomorphic liposarcoma occurring in the small intestine.
- Histopathological analysis confirmed the diagnosis of pleomorphic liposarcoma.
Implications:
- This unusual presentation underscores the necessity of including rare entities in the differential diagnosis of small bowel neoplasms.
- Accurate pathological diagnosis is crucial for appropriate patient management and treatment strategies for rare gastrointestinal tumors.

