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Early Insights From a Pharmacogenomic-Enriched Comprehensive Medication Management Program Implementation in an Adult
Murray Keogh1, Maren S Fragala, Arul Prakasam Peter
1From the Coriell Life Sciences, Philadelphia, PA (Keogh, Dr Peter, Dr Shaman); Quest Diagnostics, Secaucus, NJ (Dr Fragala, Dr Lorenz, Dr Goldberg).
Objectives:
The aims of the study are to assess adoption of a pharmacogenomic-enriched comprehensive medication management program in a self-insured employer setting and to better understand medication risks that affect employees.
Methods:
Employees were identified to be at high risk of medication mismanagement and were subsequently provided with a program and process to improve their health. DNA testing, a clinical decision support system, and pharmacists were used to identify medication safety and effectiveness issues and to recommend appropriate changes.
Results:
A total of 10.6% of the invited employees enrolled in the program. Actionable recommendations were suggested by pharmacists for 85.8% of employees who completed the program, averaging 5.2 recommendations per person.
Conclusions:
Implementation of a PGx + CMM program in a self-insured employer setting is feasible, detects risks in prescription regimens, and offers opportunities to improve medication management and reduce the burden of healthcare expenses.
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