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Overcoming technological barriers in microfluidics: Leakage testing.
Vania Silverio1,2, Suvajyoti Guha3, Armelle Keiser4
1Instituto de Engenharia de Sistemas e Computadores para os Microsistemas e as Nanotecnologias, INESC MN, Lisboa, Portugal.
Frontiers in Bioengineering and Biotechnology
|September 26, 2022
Summary
Standardized leakage testing is crucial for microfluidic devices, including Lab-on-Chip and Organ-on-Chip systems. Developing common protocols will ensure quality, safety, and commercialization of these revolutionary life science technologies.
Area of Science:
- Biomedical Engineering
- Microfluidics Technology
- Life Sciences Innovation
Background:
- Microfluidic devices, including Lab-on-Chip (LoC) and Organ-on-Chip (OoC) systems, are revolutionizing life sciences and biomedical fields.
- Despite their potential, standardized test methods for manufacturing, performance, and safety validation are lacking.
- Leakage testing is a critical, yet challenging, area requiring community consensus and standardized protocols.
Conclusions:
- Establishing widely supported leakage test protocols is essential for microfluidic device development and commercialization.
- Further discussion and development of gas and liquid leakage test standards are needed in academia and industry.
- Standardization will enhance the reliability, safety, and market adoption of microfluidic technologies.
