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Updated: Aug 27, 2025

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Improving hepatitis C screening and access to treatment
Ryan Alberts1, AnnMarie Zimmermann, Anthony Martinez
1Ryan Alberts practices at Universal Primary Care in Olean, N.Y. AnnMarie Zimmermann is medical director of the Southern Tier Community Health Center Network in Olean, N.Y. Anthony Martinez is an associate professor of medicine in the Jacobs School of Medicine at the University at Buffalo (N.Y.) and medical director of hepatology at Erie County Medical Center in Buffalo, N.Y. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
The rising prevalence of opioid use disorder and injection drug use has resulted in an increasing incidence of chronic hepatitis C virus (HCV) infection. Although older adults historically have represented the bulk of HCV infections in the United States, demographics have shifted and most new infections are presenting in younger patients. As a result, screening guidelines for HCV have evolved, moving toward a near-universal screening paradigm. Rates of screening and linkage to care remain low, attributed to the fact that underserved populations are disproportionately affected and often have limited access to specialty care. Collaborative models to treat HCV using primary care providers have been proposed to facilitate linkage to care and reduce transmission.
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