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Right Heart Function in Cardiorenal Syndrome

Tilmann Kramer1,2, Paul Brinkkoetter3,4,5, Stephan Rosenkranz6,3,5

  • 1Klinik III Für Innere Medizin, Herzzentrum Der Universität Zu Köln, Köln, Germany. tilmann.kramer@uk-koeln.de.

Current Heart Failure Reports
|September 27, 2022
PubMed

Insights

Cardiorenal syndrome (CRS) impacts heart failure outcomes, highlighting the need to monitor right heart and kidney function. Early assessment and tailored treatments are crucial for managing this complex cardiorenal interplay.

Area of Science:

  • Cardiology
  • Nephrology
  • Cardiorenal Medicine

Background:

  • Cardiorenal syndrome (CRS) in heart failure patients is linked to adverse outcomes.
  • Systemic venous congestion and elevated central venous pressure are key contributors to CRS but often overlooked.
  • Right heart function critically influences the hemodynamic balance in CRS.

Approach:

  • This systematic review synthesizes novel diagnostic and therapeutic strategies for CRS.
  • Focuses on emerging tools for assessing right heart and renal function.
  • Emphasizes the importance of monitoring hemodynamic and CRS profiles.

Key Points:

  • Right heart function assessment is vital for managing cardiorenal syndrome.
  • Emerging tools like renal Doppler ultrasonography and novel biomarkers aid in monitoring.
  • Tailoring treatment based on hemodynamic and CRS profiles can preserve renal function.

Conclusions:

  • Comprehensive assessment and monitoring of right heart and kidney function are essential for improving clinical outcomes in heart failure patients with CRS.
  • Novel diagnostic and therapeutic paradigms are crucial for managing the increasing population with CRS.
  • Understanding the interorgan crosstalk in CRS guides clinical management and treatment strategies.
Abstract

Keywords:
BiomarkersCardiorenal syndromePulmonary arterial hypertensionPulmonary hypertensionRenal dysfunctionRight heart failureRight heart functionTreatment approachesVenous congestion

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