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Updated: Aug 27, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

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Right Heart Function in Cardiorenal Syndrome.

Tilmann Kramer^1,2, Paul Brinkkoetter^3,4,5, Stephan Rosenkranz^6,3,5

¹Klinik III Für Innere Medizin, Herzzentrum Der Universität Zu Köln, Köln, Germany. tilmann.kramer@uk-koeln.de.

Current Heart Failure Reports

|September 27, 2022

Summary

Cardiorenal syndrome (CRS) impacts heart failure outcomes, highlighting the need to monitor right heart and kidney function. Early assessment and tailored treatments are crucial for managing this complex cardiorenal interplay.

Keywords:

Biomarkers Cardiorenal syndrome Pulmonary arterial hypertension Pulmonary hypertension Renal dysfunction Right heart failure Right heart function Treatment approaches Venous congestion

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Published on: December 2, 2016

Area of Science:

Cardiology
Nephrology
Cardiorenal Medicine

Background:

Cardiorenal syndrome (CRS) in heart failure patients is linked to adverse outcomes.
Systemic venous congestion and elevated central venous pressure are key contributors to CRS but often overlooked.
Right heart function critically influences the hemodynamic balance in CRS.

Approach:

This systematic review synthesizes novel diagnostic and therapeutic strategies for CRS.
Focuses on emerging tools for assessing right heart and renal function.
Emphasizes the importance of monitoring hemodynamic and CRS profiles.

Key Points:

Right heart function assessment is vital for managing cardiorenal syndrome.
Emerging tools like renal Doppler ultrasonography and novel biomarkers aid in monitoring.
Tailoring treatment based on hemodynamic and CRS profiles can preserve renal function.

Conclusions:

Comprehensive assessment and monitoring of right heart and kidney function are essential for improving clinical outcomes in heart failure patients with CRS.
Novel diagnostic and therapeutic paradigms are crucial for managing the increasing population with CRS.
Understanding the interorgan crosstalk in CRS guides clinical management and treatment strategies.