Related Experiment Video

Updated: Aug 27, 2025

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

19.7K

Higher visceral adiposity index is associated with increased likelihood of abdominal aortic calcification

Zheng Qin1, Luojia Jiang2, Jiantong Sun3

  • 1Department of Nephrology, National Clinical Research Center for Geriatrics, Med+ Biomaterial Institute of West China School of Medicine, West China Hospital of Sichuan University, China.

Clinics (Sao Paulo, Brazil)
|September 27, 2022
PubMed

Insights

Higher visceral adiposity, measured by the Visceral Adiposity Index (VAI), is linked to increased abdominal aortic calcification (AAC) and a greater risk of severe AAC in US adults.

Area of Science:

  • Cardiovascular Health
  • Metabolic Syndrome
  • Radiology

Background:

  • Visceral adiposity negatively impacts cardiovascular health.
  • The relationship between the Visceral Adiposity Index (VAI) and Abdominal Aortic Calcification (AAC) remains unexplored.
  • This study investigates the association between VAI and AAC in US adults.

Purpose of the Study:

  • To examine the association between the Visceral Adiposity Index (VAI) and Abdominal Aortic Calcification (AAC).
  • To determine if increased visceral adiposity correlates with the presence and severity of AAC.

Main Methods:

  • Utilized cross-sectional data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES).
  • Included participants with complete VAI and AAC data.
  • Employed weighted multivariable and logistic regression analyses, including subgroup analysis and interaction tests.

Main Results:

  • Higher VAI tertiles were associated with increased mean AAC scores and a higher prevalence of severe AAC.
  • A positive association was found between VAI and AAC score (β=0.04) and severe AAC (OR=1.04) in the fully adjusted model.
  • Participants in the highest VAI tertile had significantly higher AAC scores and a 68% increased risk of severe AAC compared to the lowest tertile.

Conclusions:

  • Visceral adiposity, as indicated by VAI, is significantly associated with higher AAC scores.
  • Elevated VAI is linked to an increased likelihood of developing severe Abdominal Aortic Calcification.
  • The findings highlight VAI as a potential indicator for cardiovascular risk related to aortic calcification.
Abstract

Keywords:
Abdominal aortic calcificationCross-sectional studyVascular calcificationVisceral adiposity index

More Related Videos

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model05:14

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

Published on: November 18, 2022

4.0K
Author Spotlight: The Significance of Isolation, Culture, and Adipogenic Induction of SVF-Derived Preadipocytes from Mouse Perivascular Adipose Tissue06:56

Author Spotlight: The Significance of Isolation, Culture, and Adipogenic Induction of SVF-Derived Preadipocytes from Mouse Perivascular Adipose Tissue

Published on: July 21, 2023

2.4K

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
107
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
647
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
19
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
47
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
32
Abdominal Aorta01:25

Abdominal Aorta

Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
1.1K