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Updated: Aug 27, 2025

Laparoscopic Common Bile Duct Exploration Followed by Primary Suture Using a Modified Bile Duct Incision
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Published on: May 2, 2025

221

Developments in the Diagnosis and Management of Cholecystoenteric Fistula

Ying-Yu Liu1, Shi-Yuan Bi1, Quan-Run He1

  • 1Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
|September 27, 2022
PubMed

Insights

Cholecystoenteric fistula (CEF) is a rare gallbladder complication. Early diagnosis of CEF is crucial for effective treatment, as it is often difficult to detect preoperatively and can lead to complications.

Area of Science:

  • Gastroenterology
  • Surgical Complications

Background:

  • Cholecystoenteric fistula (CEF) is a rare complication of gallstones.
  • CEF involves pathological perforations between the gallbladder and adjacent gastrointestinal tract.
  • First described in 1645, CEF remains a diagnostic challenge.

Purpose of the Study:

  • To review the etiology, symptoms, diagnosis, and treatment of cholecystoenteric fistulas.
  • To highlight the challenges in preoperative diagnosis of CEF.
  • To emphasize the importance of early CEF diagnosis for patient outcomes.

Main Methods:

  • A comprehensive literature search was performed using PubMed.
  • Included historical and current peer-reviewed studies on CEF.
  • Studies were selected based on predefined criteria.

Main Results:

  • Clinical manifestations of CEF are typically latent.
  • Preoperative diagnosis of CEF is difficult despite advanced imaging.
  • CEF is frequently discovered perioperatively or intraoperatively.

Conclusions:

  • Inadequate preoperative preparation can lead to gastrointestinal injury and bleeding.
  • CEF diagnosis and management remain controversial and often unreported.
  • Early diagnosis of CEF is essential for effective treatment and improved patient outcomes.

Keywords:
Bouveret syndromeCholecystoenteric fistulaGallstone ileusGallstonesLaparoscopic cholecystectomy

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