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[Cerebral venous thrombosis associated with COVID-19]
D R Safina1, E I Gismatullina1, R G Esin1,2
1Kazan (Volga region) Federal University, Kazan, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|September 28, 2022
Summary
Cerebral venous thrombosis (CVT) affects 1-1.5% of COVID-19 patients. A rare vaccine side-effect, vaccine-induced immune thrombotic thrombocytopenia (VITT), also causes CVT, as seen in a Sputnik V recipient.
Area of Science:
- Neurology
- Immunology
- Vaccinology
Background:
- Cerebral venous thrombosis (CVT) is a known complication of COVID-19, occurring in 1-1.5% of cases.
- Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a newly identified syndrome linked to COVID-19 vaccination.
- VITT is characterized by thrombosis, often in cerebral veins, and thrombocytopenia.
Observation:
- This article reviews the emerging understanding of VITT and its association with CVT.
- A clinical case of CVT developing within a month post-Sputnik V vaccination is presented.
- The patient's presentation highlights the potential link between COVID-19 vaccination and thrombotic events.
Findings:
- COVID-19 is associated with an increased risk of cerebral venous thrombosis.
- Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but serious adverse event following certain COVID-19 vaccines.
- CVT can manifest as a complication of VITT, necessitating careful differential diagnosis.
Implications:
- Increased awareness of VITT is crucial for clinicians managing patients after COVID-19 vaccination.
- Prompt diagnosis and management of VITT are essential to improve patient outcomes.
- Further research is needed to fully understand the pathophysiology and long-term effects of VITT.
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