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Renal Transplantation Could Reverse Dialysis-Associated Porphyria.
Sasanka K Barua1, Sachinkumar Patel1, Debanga Sarma1
1Urology, Gauhati Medical College & Hospital, Guwahati, IND.
Cureus
|September 30, 2022
Summary
Pseudoporphyria (PP) is a rare skin condition often seen in dialysis patients. Renal transplantation effectively cured a patient with drug-resistant pseudoporphyria, suggesting it as a definitive treatment.
Area of Science:
- Dermatology
- Nephrology
- Genetics
Background:
- Pseudoporphyria (PP) is a photodistributed bullous dermatosis mimicking porphyria cutanea tarda (PCT) but without porphyrin abnormalities.
- It is often observed in patients with end-stage renal disease undergoing hemodialysis, termed 'bullous dermatosis of hemodialysis.'
- Conventional treatments for pseudoporphyria have shown limited efficacy.
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