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Updated: Aug 27, 2025

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
LPdCl2(amine) complexes supported by terphenyl phosphanes: applications in aryl amination reactions
Nazaret Santamaría1, Clara Velasco1, Mario Marín1
1Departamento de Química Inorgánica, Universidad de Sevilla, Aptdo 1203, 41071 Sevilla, Spain. mnicasio@us.es.
Abstract:
Despite the excellent catalytic properties display by NHC-Pd-PEPPSI complexes in cross-coupling, phosphane analogs have been barely screened. In this work, we report the synthesis and characterization of a series of LPdCl2(amine) complexes bearing dialkylterphenyl phosphanes (PR2Ar') and pyridine or morpholine ligands. The novel compounds have been tested as precatalysts in aryl amination reactions. The complex [(PCyp2ArXyl2)PdCl2(morpholine)] shows the best catalytic activity allowing the room-temperature coupling of aryl bromides and chlorides with aniline.
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