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Updated: Aug 21, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Transition Metal-Free Direct Trifluoromethylation of 2,3-Dihydropyridin-4(1H)-ones at Room Temperature

Yi-Yun Yu1, Adwait R Ranade2, Gunda I Georg1,2

  • 1Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, United States.

Advanced Synthesis & Catalysis
|August 20, 2026
PubMed

Keywords:
C-H activationCross-couplingHeterocyclesRadicalsTrifluoromethylation

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