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Updated: Jan 20, 2026

Chemical Modification of the Tryptophan Residue in a Recombinant Ca2+-ATPase N-domain for Studying Tryptophan-ANS FRET
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Chemical Modification of the Tryptophan Residue in a Recombinant Ca2+-ATPase N-domain for Studying Tryptophan-ANS FRET

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Synthesis of 4,6-Difluoro-Tryptophan as a Probe for Protein 19F NMR

Christina M Monnie1, Iker Hernández2, Raixie Meléndez-Pacheco1

  • 1Department of Structural Biology, University of Pittsburgh School of Medicine, 3501 Fifth Ave., Pittsburgh, PA 15261, USA.

Advanced Synthesis & Catalysis
|January 19, 2026
PubMed
Abstract

Keywords:
Amino acid synthesisFluorinated tryptophansGramines couplingProtein 19F NMR

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