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Imaging Cell Viability on Non-transparent Scaffolds — Using the Example of a Novel Knitted Titanium Implant
Published on: September 7, 2016
Explant analysis of a Discocerv cervical disc: A case study for a ceramic-on-ceramic cervical disc
Göksu Kandemir1, Andrew Bowey2, Cyrus Jensen3
1School of Engineering, Newcastle University, Newcastle Upon Tyne, UK.
Abstract:
Explant analyses are key to better understanding the effectiveness of medical implants in replacing natural joints. For the first time, an explanted Discocerv cervical disc was examined. The implant utilised the articulation of a caudal zirconia cup (inferior component) and a cephalic alumina head (superior component). The articulating surface of the superior alumina head had an average surface roughness of 0.016 ± 0.003 μm (Sa) and the articulating surface of the inferior zirconia cup had an average surface roughness of 0.015 ± 0.002 μm (Sa). Both articulating surfaces had negative skewness, indicating the removal of local peaks. The difference between the average surface roughness of the components was not significant (p-value: 0.741). Dark grey marks were observed on both of the articulating surfaces, which were found to be adhered titanium debris that was generated due to component impingement. This titanium debris may explain the small amount of metallosis that was reported at explantation. Some transfer of zirconium to the alumina articulating surface was also seen.
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