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Brain Injury in Infants Evaluated for, But Not Treated with, Therapeutic Hypothermia

Kirsten R Thiim1, Aisling A Garvey2, Elizabeth Singh1

  • 1Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA.

The Journal of Pediatrics
|September 30, 2022
PubMed

Defining neonatal encephalopathy clinically to qualify for therapeutic hypothermia is challenging. This study examines magnetic resonance imaging outcomes of 39 infants who were evaluated and not cooled using criteria inclusive of mild encephalopathy. Infants evaluated for therapeutic hypothermia are at risk for brain injury and may benefit from neuroimaging and follow-up.

Keywords:
hypoxic–ischemic encephalopathymagnetic resonance imagingneonatal encephalopathy

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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