Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

180
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
180

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recalcitrant Basal Cell Carcinoma after Grenz Ray Therapy: Introduction of High-Intensity Focused Ultrasound for Minimally Invasive Management.

Case reports in dermatology·2024
Same author

Unusual Acute Appendicitis Complicated by Sepsis, Evisceration, and Ileostomy: A Case Report.

Cureus·2024
Same author

Non-bacterial Thrombotic Endocarditis (NBTE) in the Absence of Malignancy or Lupus Anticoagulant/Antiphospholipid Antibodies: A Case Report.

Cureus·2024
Same author

High Intensity Focused Ultrasound (20 MHz) and Cryotherapy as Therapeutic Options for Granuloma Annulare and Other Inflammatory Skin Conditions.

Dermatology and therapy·2024
Same author

Healing Process after High-Intensity Focused Ultrasound Treatment of Benign Skin Lesions: Dermoscopic Analysis and Treatment Guidelines.

Journal of clinical medicine·2024
Same author

Lead-Free Piezoelectric Transducers.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2023

Related Experiment Video

Updated: Aug 27, 2025

Controllable Nucleation of Cavitation from Plasmonic Gold Nanoparticles for Enhancing High Intensity Focused Ultrasound Applications
08:19

Controllable Nucleation of Cavitation from Plasmonic Gold Nanoparticles for Enhancing High Intensity Focused Ultrasound Applications

Published on: October 5, 2018

6.5K

Lead-Free HIFU Transducers.

Tomasz Zawada1, Torsten Bove1, Konstantin Astafiev2

  • 1TOOsonix A/S, Hoersholm, Denmark.

Ultrasound in Medicine & Biology
|September 30, 2022
PubMed
Summary

High-intensity focused ultrasound transducers using lead-free sodium bismuth titanate (NBT) piezoceramics demonstrate stable performance. These NBT-based transducers show promising efficiency and thermal stability for high-power therapeutic ultrasound applications.

Keywords:
Lead free, High-intensity focused ultrasound, Electro-acoustic efficiencyTransducer, Piezoelectric, Tissue-mimicking phantom

More Related Videos

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases
05:56

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Published on: January 9, 2019

7.9K
Real-time Monitoring of High Intensity Focused Ultrasound HIFU Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound HMIFU
07:38

Real-time Monitoring of High Intensity Focused Ultrasound HIFU Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound HMIFU

Published on: November 3, 2015

10.1K

Related Experiment Videos

Last Updated: Aug 27, 2025

Controllable Nucleation of Cavitation from Plasmonic Gold Nanoparticles for Enhancing High Intensity Focused Ultrasound Applications
08:19

Controllable Nucleation of Cavitation from Plasmonic Gold Nanoparticles for Enhancing High Intensity Focused Ultrasound Applications

Published on: October 5, 2018

6.5K
Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases
05:56

Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases

Published on: January 9, 2019

7.9K
Real-time Monitoring of High Intensity Focused Ultrasound HIFU Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound HMIFU
07:38

Real-time Monitoring of High Intensity Focused Ultrasound HIFU Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound HMIFU

Published on: November 3, 2015

10.1K

Area of Science:

  • Materials Science
  • Acoustics
  • Biomedical Engineering

Background:

  • Traditional high-power therapeutic ultrasound often relies on lead-based piezoelectric materials like PZT.
  • Lead-free alternatives are sought to address environmental and health concerns associated with lead.
  • Sodium bismuth titanate (NBT) based piezoceramics present a potential lead-free solution.

Purpose of the Study:

  • To evaluate the performance and stability of high-intensity focused ultrasound (HIFU) transducers operating at 4 MHz.
  • To characterize lead-free piezoceramics from the NBT family (Pz12X) for transducer applications.
  • To assess the electro-acoustic efficiency and thermal behavior of NBT-based transducers under high power conditions.

Main Methods:

  • Fabrication and characterization of 4 MHz HIFU transducers using NBT-based piezoceramics (Pz12X).
  • Evaluation of electro-acoustic efficiency dependence on acoustic power levels up to 30 W.
  • Assessment of transducer stability through extended power burst cycling (95,000 bursts).
  • Simultaneous measurement of input electric power, output acoustic power, and piezoelectric component temperature.

Main Results:

  • Initial electro-acoustic efficiency of NBT transducers was approximately 50%, slightly dropping to 42% at 10 W input power, with stable and reversible performance.
  • Transducers maintained electro-acoustic performance after extensive power burst cycling (95 x 10^3 bursts at 10 W).
  • Maximum operating temperature remained below 60°C during high-power bursts, well below the material's de-poling temperature (~85°C).

Conclusions:

  • Lead-free NBT-based piezoceramics are a viable and promising alternative to lead-based PZT materials for high-power therapeutic ultrasound.
  • NBT transducers exhibit robust electro-acoustic efficiency and thermal stability suitable for demanding applications.
  • The developed transducers meet operational limits for high-power ultrasound, offering a safer, lead-free option.