Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hypodermis

Hypodermis

The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Musculoskeletal Burden in German Equestrians: Hip-Specific Symptoms and Risk Factors.

International journal of sports medicine·2026

Same author

A deep-learning framework reveals whole-body perturbations at cell level.

Nature·2026

Same author

Long-term clinical and radiographic outcomes after locking plate fixation of proximal humerus fractures: a 6-year follow-up study.

JSES international·2026

Same author

Evaluation of Intravenous Administration of Anti-Infective Agents and Documentation Quality in Orthopedics and Trauma Surgery: A Quantitative Study on Discrepancies Between Physician Prescriptions and Nursing Records.

Antibiotics (Basel, Switzerland)·2026

Same author

Prevention of surgical site infections in lower limb fracture fixation and elective arthroplasty: a systematic review and meta-analysis of decolonization and skin antisepsis strategies.

Antimicrobial resistance and infection control·2026

Same author

The sciatic gliding space.

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft·2026

Search research articles

Related Experiment Video

Updated: Aug 27, 2025

Identification and Dissection of Diverse Mouse Adipose Depots

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

The subpopliteal fat body.

Christoph Hellmund¹, Pierre Hepp², Hanno Steinke¹

¹Institut für Anatomie, Universität Leipzig, Liebigstr. 13, 04103 Leipzig, Germany.

Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft

|October 1, 2022

Summary

This summary is machine-generated.

Researchers identified a new subpopliteal fat body (SFB) in the knee, crucial for popliteus muscle function. This functional fat may explain deep lateral knee pain when compressed.

Keywords:

Fibula Fossa Popliteal Popliteal artery Popliteus muscle Subpopliteal recess Tibia fat water

More Related Videos

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

Published on: February 18, 2015

Related Experiment Videos

Last Updated: Aug 27, 2025

Identification and Dissection of Diverse Mouse Adipose Depots

Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images

Published on: February 18, 2015

Area of Science:

Anatomy
Histology
Biomechanics

Background:

The knee's complex anatomy includes fatty tissues that play vital roles.
While the ventral Hoffa's fat pad is well-researched, dorsal knee fat bodies remain less understood.
This study focuses on a previously undescribed dorsal fat body, the subpopliteal fat body (SFB).

Purpose of the Study:

To describe the anatomy and location of a newly identified subpopliteal fat body (SFB) in the knee.
To investigate the neurovascular structures associated with the SFB.
To elucidate the potential function and clinical relevance of the SFB.

Main Methods:

Dissection of 11 fresh knee specimens, focusing on the popliteus muscle and surrounding structures.
Histological examination including HE staining and neurofilament immunostaining.
Identification of the SFB using MRI and plastination techniques.

Main Results:

A distinct subpopliteal fat body (SFB) was identified ventral to the popliteus muscle, attached to the tibia and muscle.
Neurovascular bundles, including arterial, venous, and tibial nerve branches, were observed within the SFB.
The SFB was visualized using MRI and plastination, confirming its presence and anatomical relations.

Conclusions:

The SFB likely serves as a gliding space for the popliteus muscle, facilitating its movement over the tibia.
The presence of neurovascular bundles suggests the SFB may be implicated in deep lateral knee pain syndromes when compressed.
This functional fat tissue is comparable to the well-known Hoffa's fat pad and warrants further investigation.