Electron microscopy of biopsies from bronchogenic neoplasms

Bronchial biopsies were investigated by light microscopy (LM) and electron microscopy (EM) with the aim to evaluate if EM could contribute to the LM tumour type diagnosis. Fourty-three pairs of biopsies were comparable. A histogenetic typing, especially of light microscopically undifferentiated and unclassifiable carcinomas, was possible by EM. However, when considering the therapeutical possibilities, at present time, LM tumour classification must be regarded as fully sufficient.