Angiosarcoma of the breast. A report of three cases

The histopathologic and clinical features of 3 breast angiosarcomas were presented. The microscopic patterns were heterogeneous, comprising vascular structures in various degrees of differentiation and solid cellular proliferations, the proportion of which varied from tumor to tumor. All 3 tumors were classified in the third group of angiosarcomas. One widely-excised tumor recurred and developed lung metastases 11 months after mastectomy and during a polychemotherapy. The other 2 patients were well and free from disease 9/11 months after the surgical and radiation therapy.