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Monitoring disease progression in childhood bronchiectasis

Kathryn A Ramsey1, André Schultz1,2

  • 1Wal-yan Respiratory Research Centre, Telethon Kids Institute, University of Western Australia, Perth, WA, Australia.

Frontiers in Pediatrics
|October 3, 2022
PubMed

Insights

Monitoring childhood bronchiectasis is crucial for early intervention and preventing lung decline. This review covers key methods like imaging and lung function tests for effective disease management.

Area of Science:

  • Pulmonology
  • Pediatric Respiratory Medicine

Background:

  • Bronchiectasis, excluding cystic fibrosis, is a chronic lung condition marked by airway dilation and frequent respiratory symptoms.
  • It significantly impacts patients' quality of life and life expectancy, often necessitating hospitalizations for exacerbations.

Purpose of the Study:

  • To review current methods for monitoring disease progression in pediatric bronchiectasis.
  • To highlight the importance of early diagnosis and management in preventing long-term respiratory decline.

Main Methods:

  • The review synthesizes information on various monitoring techniques.
  • Methods discussed include lung imaging, respiratory function tests, patient-reported outcomes, exacerbation tracking, sputum biomarkers, and nutritional assessments.

Main Results:

  • Effective monitoring aids in early detection of exacerbations for timely treatment.
  • It enables tracking disease progression for prognosis and assessing treatment efficacy.

Conclusions:

  • Comprehensive monitoring is essential for optimizing quality of life and potentially reversing disease in children with bronchiectasis.
  • A multi-faceted approach combining clinical, functional, and patient-reported data is recommended.

Keywords:
biomarkersbronchiectasischildrenexacerbationsimaginglung functionmonitoringsymptoms

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