Related Experiment Video

Updated: Aug 26, 2025

Author Spotlight: Enhancing Understanding and Treatment Strategies with the NEC-on-a-Chip Model
06:51

Author Spotlight: Enhancing Understanding and Treatment Strategies with the NEC-on-a-Chip Model

Published on: July 28, 2023

1.4K

Intermittent Volvulus with Obstruction Due to a Meckel's Diverticulum and Band Presenting as Feeding Intolerance in a

Suresh Kotinatot1, Shiva Shankar1, Muhammad Ba Ath2

  • 1Department of Neonatology, Al Jalila Children's Speciality Hospital, Dubai, UAE.

Oman Medical Journal
|October 3, 2022
PubMed

Insights

Trisomy 13 increases susceptibility to Meckel's diverticulum, a rare condition. This case highlights a neonate with feeding intolerance due to Meckel's diverticulum causing bowel obstruction.

Area of Science:

  • Pediatric Surgery
  • Medical Genetics
  • Neonatology

Background:

  • Trisomy 13 (Patau syndrome) is a severe genetic disorder associated with congenital anomalies.
  • Meckel's diverticulum is a common congenital anomaly of the gastrointestinal tract, typically asymptomatic.
  • Symptomatic Meckel's diverticulum in neonates, especially those with trisomy 13, is exceptionally rare.

Observation:

  • A neonate diagnosed with trisomy 13 presented with significant feeding intolerance.
  • Clinical signs included persistent bilious aspirates, indicating upper gastrointestinal obstruction.
  • Diagnostic workup revealed a Meckel's diverticulum complicated by a peritoneal band.

Findings:

  • The Meckel's diverticulum and associated peritoneal band led to intermittent volvulus.
  • This mechanical obstruction resulted in the observed feeding intolerance and bilious aspirates.
  • The combination of trisomy 13 and symptomatic Meckel's diverticulum represents an extremely rare clinical scenario.

Implications:

  • This case underscores the importance of considering Meckel's diverticulum in neonates with trisomy 13 presenting with gastrointestinal issues.
  • Early diagnosis and surgical intervention are crucial for managing obstructive complications in this vulnerable population.
  • Further research may elucidate the specific mechanisms linking trisomy 13 and gastrointestinal complications like symptomatic Meckel's diverticulum.

Keywords:
BileMeckel DiverticulumTrisomy 13 SyndromeUnited Arab EmiratesVolvulus

More Related Videos

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis05:39

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

Published on: November 30, 2021

3.7K
Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

2.0K

Related Concept Videos

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
257
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
146
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
244
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
131
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
158
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
430