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Updated: Aug 26, 2025

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
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Symptom Control Research.

Vyjeyanthi S Periyakoil1,2, Charles F von Gunten3, Eduardo Bruera4

  • 1Department of Medicine, Stanford University, Palo Alto, California, USA.

Journal of Palliative Medicine
|October 3, 2022
PubMed
Summary
This summary is machine-generated.

Symptom control research in hospice and palliative care is underdeveloped. Future progress requires conducting new research, establishing organized research groups, and training clinicians in research methods to advance evidence-based practices.

Keywords:
clinical trialsgovernment-funded researchhospicepalliative carerandomized control trialssymptom control research

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Area of Science:

  • Palliative Care
  • Symptom Management Research

Background:

  • Symptom control research is crucial but underdeveloped in hospice and palliative care.
  • Current practices often lack the support of rigorous scientific evidence, including randomized controlled trials.

Purpose of the Study:

  • To identify key issues and future directions for symptom control research in palliative care over the next 25 years.
  • To emphasize the need for advancing evidence-based practices through dedicated research efforts.

Main Methods:

  • Expert consensus and identification of research gaps.
  • Evaluation of the current state of palliative care science.
  • Recommendations for future research infrastructure and training.

Main Results:

  • Significant need for new research beyond existing evidence.
  • Barriers include insufficient self-discipline in evaluating current palliative care science.
  • Commitment to organized research groups and clinical trials networks is essential.

Conclusions:

  • Advancing symptom control in palliative care necessitates a proactive research agenda.
  • Integrating symptom control research with disease-directed research offers a promising path forward.
  • Investing in training for clinicians and researchers in research methods is critical for future advancements.