Noncardiogenic pulmonary edema following hydrochlorothiazide ingestion

A 57-year-old woman presented in severe respiratory distress 30 minutes after ingesting hydrochlorothiazide. Pulmonary edema was evident clinically and radiographically. A noncardiogenic etiology was suggested by the lack of jugular venous distention, S3 gallop, or pedal edema, and the presence of a normal cardiac silhouette on chest radiograph. The patient's pulmonary edema remitted with supportive therapy.