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Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
08:49

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

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Outcomes of pediatric patients supported with ventricular assist devices single center experience

Hsun-Yi Fu1, Heng-Wen Chou2, Chien-Heng Lai2

  • 1Department of Cardiovascular Surgery, Department of Surgery, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|October 3, 2022
PubMed

Insights

Pediatric ventricular assist device (VAD) use is increasing. Our hospital reports favorable outcomes for pediatric VAD patients, with 72.7% achieving positive results at one month.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Biomedical Engineering

Background:

  • Increasing use of pediatric ventricular assist devices (VADs) globally.
  • Limited participation of Asian pediatric heart centers in international VAD registries.
  • Need to report outcomes from non-Western centers.

Purpose of the Study:

  • To report the outcomes of pediatric VAD implantation at our institution.
  • To contribute data from an Asian pediatric heart center to the global understanding of VAD therapy.
  • To evaluate the safety and efficacy of VADs in a pediatric population.

Main Methods:

  • Retrospective analysis of all pediatric patients (<18 years) who received a VAD between 2008 and 2021.
  • Data collection on patient demographics, diagnosis, VAD type, INTERMACS profile, duration on support, and outcomes.
  • Analysis of survival rates, causes of death, and recovery status.

Main Results:

  • 33 pediatric patients received VADs, primarily for dilated cardiomyopathy (n=16) and acute fulminant myocarditis (n=9).
  • Paracorporeal continuous-flow pumps were most common (n=27), with most patients in INTERMACS profile 1 (n=24).
  • Positive outcomes (alive on device, bridge to transplantation/recovery) were observed in 72.7% at 1 month, 67.7% at 3 months, and 67.7% at 6 months. Neurological complications were the leading cause of death within the first month.

Conclusions:

  • Pediatric VAD implantation at our institution demonstrated favorable outcomes.
  • Early VAD support can be effective for critically ill pediatric heart failure patients.
  • Further research is needed to compare outcomes across different centers and VAD technologies.
Abstract

Keywords:
Heart failurePediatricTransplantVentricular assist device

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