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Updated: Aug 26, 2025
09:49
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
10.1K
Dosimetry in Radiopharmaceutical Therapy.
Joe O'Donoghue1, Pat Zanzonico1, John Humm1
1Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Summary
Radiopharmaceutical therapy is expanding with new agents. Patient-specific internal dosimetry offers personalized treatment optimization, improving therapeutic radiopharmaceutical applications.
Area of Science:
- Nuclear Medicine
- Medical Physics
Background:
- Radiopharmaceutical therapy is a growing field with novel agents.
- Increasing interest exists in personalizing therapy using internal dosimetry.
Purpose of the Study:
- To discuss the current state of internal dosimetry for radiopharmaceutical therapy.
- To explore the integration of dosimetry in optimizing patient treatment.
Main Methods:
- Review of internal dosimetry principles and methods.
- Discussion of advantages and disadvantages of dosimetry calculations.
- Description of patient-specific dosimetry workflow.
Main Results:
- Internal dosimetry is multifaceted and evolving.
- Patient-specific dosimetry enables personalized radiopharmaceutical therapy.
Conclusions:
- Internal dosimetry is crucial for optimizing radiopharmaceutical therapy.
- Future prospects involve further integration of dosimetry for improved patient outcomes.
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