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Published on: February 23, 2014
Supraglottitis and Hemophilus parainfluenzae: pathogenic potential of the organism
Abstract:
Hemophilus parainfluenzae may be a normal inhabitant of the pharynx, but it can have pathogenic potential elsewhere in the body. It has been identified as a cause of bacteremia and meningitis. The case discussed here represents the first report of H parainfluenzae-induced supraglottitis in a child. In reviewing its pathogenic potential in the upper respiratory tract, it appears that its major effect could be the ability to transfer ampicillin resistance to ampicillin-susceptible Hemophilus influenzae.
Insights
Hemophilus parainfluenzae can cause serious infections like bacteremia and meningitis. This case highlights its role in childhood supraglottitis and potential ampicillin resistance transfer.
Area of Science:
- Pediatric infectious diseases
- Bacteriology
- Microbial pathogenesis
Background:
- Hemophilus parainfluenzae is typically a pharyngeal commensal.
- This bacterium has been linked to invasive infections, including bacteremia and meningitis.
- Its role in upper respiratory tract infections, particularly in children, is less understood.
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