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Bromelain-based enzymatic burn debridement: Spanish multidisciplinary consensus.
Jordi Serracanta1, Jacinto Baena2, José R Martinez-Mendez3
1Department of Plastic Surgery and Burn Center, Vall d'Hebron University Hospital, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
European Journal of Plastic Surgery
|October 4, 2022
Summary
This updated consensus provides expert recommendations on bromelain-based enzymatic debridement (NexoBrid®) for burn injuries. It integrates broader clinical experience to refine treatment guidelines for better patient outcomes.
Area of Science:
- Wound Healing
- Dermatology
- Surgical Innovation
Background:
- Bromelain-based enzymatic debridement is increasingly adopted by burn specialists.
- This document updates the 2017 Spanish consensus on NexoBrid® for burn injuries.
- It incorporates expanded clinical expertise from surgeons, intensivists, and anesthesiologists.
Purpose of the Study:
- To provide an updated consensus on the use of NexoBrid® for enzymatic debridement in burn care.
- To integrate the clinical experience of a multidisciplinary expert panel.
- To refine existing guidelines based on current practice.
Main Methods:
- A modified Delphi methodology was employed.
- A 38-topic survey was administered in two rounds to experts.
- Consensus was sought across six domains, including indications, pain management, and wound care.
Main Results:
- Initial consensus was reached on 13 of 38 statements in the first round.
- A high consensus rate (97.2%) was achieved on the remaining 25 statements in the second round.
- The study achieved strong agreement on most aspects of NexoBrid® application and management.
Conclusions:
- The updated consensus offers recommendations for bromelain-based enzymatic debridement with NexoBrid® in Spain.
- It reflects the collective clinical experience of plastic surgeons, intensivists, and anesthesiologists.
- Further research is recommended to validate and refine these consensus statements.
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