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Updated: Aug 26, 2025

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
Cataract surgery in patients with underlying keratoconus: focused review
Roberto Gonzalez-Salinas1, Jovany Jeomar Franco, José Luis Reyes-Luis
1From the Anterior Segment Surgery Department, Asociación para Evitar la Ceguera I.A.P., Mexico City, Mexico (Gonzalez-Salinas); Harvard Medical School, Boston, Massachusetts (Franco, Pineda); Cornea and Refractive Surgery Service, Massachusetts Eye and Ear, Boston, Massachusetts (Reyes-Luis, Pineda); Cornea Department, Asociación para Evitar la Ceguera I.A.P., Mexico City, Mexico (Sánchez-Huerta, de Wit-Carter); Division of Comprehensive Ophthalmology, Wilmer Eye Institute, Johns Hopkins Medicine, Baltimore, Maryland (Hernández-Quintela).
Abstract:
An underlying diagnosis of keratoconus (KC) can complicate cataract surgery. In this study, the results of a focused review of the literature pertaining to cataract surgery in patients with KC are detailed. Topics essential for the appropriate management of this patient population are discussed. First, the individual and shared epidemiology and pathophysiology of cataract and KC are reviewed. Then, the theory and approach to intraocular lens power calculation are discussed, highlighting particularities and pitfalls of this exercise when performed in patients with KC. Finally, several special-although not uncommon-management scenarios and questions are addressed, such as surgical planning in cases where corneal stabilization or tissue replacement interventions are also necessitated.
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