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The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
Published on: May 31, 2016
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[When COVID does not heal: post-COVID courses with fatigue and exercise intolerance]
Deutsche Medizinische Wochenschrift (1946)
|October 4, 2022
Summary
Post-COVID Syndrome presents diverse conditions, including organ damage and autoimmune diseases. This review focuses on fatigue and exercise intolerance, similar to myalgic encephalomyelitis/chronic fatigue syndrome after infections.
Area of Science:
- Medical research
- Infectious disease pathology
- Immunology
Background:
- Post-COVID Syndrome encompasses various conditions, including organ damage and new autoimmune diseases.
- This review specifically addresses post-COVID courses characterized by fatigue and exercise intolerance.
- These symptoms are also recognized in other infectious disease sequelae, such as myalgic encephalomyelitis/chronic fatigue syndrome.
Purpose of the Study:
- To focus on the specific subset of Post-COVID Syndrome presenting with fatigue and exercise intolerance.
- To discuss the pathological similarities between this post-COVID course and other infectious disease-related syndromes.
- To provide an overview of the current understanding of these debilitating symptoms.
Main Methods:
- Literature review of post-COVID conditions.
- Analysis of symptom presentation in Post-COVID Syndrome.
- Comparison with established syndromes like myalgic encephalomyelitis/chronic fatigue syndrome.
Main Results:
- Post-COVID Syndrome is pathobiologically diverse, not a single entity.
- Fatigue and exercise intolerance represent a significant category within Post-COVID Syndrome.
- This symptom cluster aligns with known patterns seen after other infections.
Conclusions:
- Post-COVID Syndrome requires differentiation into distinct pathobiological entities.
- Fatigue and exercise intolerance are key features of a specific post-viral syndrome.
- Understanding these similarities aids in diagnosis and management of long COVID symptoms.
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