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Updated: Aug 26, 2025

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Recent advances in optical coherence tomography for anterior segment imaging in small animals and their clinical
Lisa Beckmann1, Zhen Cai2, Mathew Margolis3
1Department of Biomedical Engineering, Northwestern University, Evanston IL, USA.
Abstract:
Anterior segment optical coherence tomography (AS-OCT) is a rapidly evolving area of OCT imaging, providing high-resolution and non-invasive volumetric imaging of the anterior segment. This review focuses on recent advances in AS-OCT imaging in small animals, which we categorize into ultrahigh-resolution, spectroscopic, magnetomotive, polarization-sensitive, and angiographic AS-OCTs. We summarize their technical foundations, review their applications to small animal imaging, and briefly discuss their current and future clinical applications.

