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Updated: Aug 26, 2025

Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
Published on: February 23, 2024
Oral health-related quality of life changes during phase 1 Class II malocclusion treatment using Frankel 2 and
Mina Pakkhesal1, Aliakbar Naghavialhosseini2, Tannaz Faali3
1Dental Research Center, Department of Community Oral Health, Dental School, Golestan University of Medical Sciences, Gorgan, Iran.
Introduction:
Orthodontic treatment procedures affect oral health-related quality of life. This study analyzed and compared the patients using the Frankel 2 Regulator (FR2) and Twin-block (TB) orthodontic appliances.
Methods:
This follow-up observational study comprised adolescents aged 10-16 years with Class II malocclusion seeking orthodontic treatment, between April and December 2019, in a private orthodontic clinic. Following the finalization of orthodontic clinical decisions, 88 patients, in a 1:1 ratio, using FR2 (n = 44) and TB (n = 44) appliances, were invited to participate in this study. An Oral Health Impact Profile-14 (OHIP-14) questionnaire was answered by the participants at 5-time points: before treatment, 1 week, 1 month, 3 months, and 6 months after wearing functional appliances. A mixed model for repeated measurements tested the OHIP-14 score mean differences over time among appliance groups and group by time interaction.
Results:
The TB group consisted of 15 males and 29 females, and the FR2 group included 21 males and 23 females. The mean age of participants was 12.18 ± 1.29 years. The mean of OHIP-14 scores in FR2 users was significantly lower than the TB appliance group at all intervals (P <0.05). Although the total score of OHIP-14 increased 1 week after appliance wearing, it declined during the 1, 3, and 6 months after wearing appliances in both groups.
Conclusions:
The results can help orthodontists better select treatment approaches by considering their effect on oral health-related quality of life.
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