Related Experiment Video

Updated: Aug 26, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.3K

Prevalence of comorbidities in deceased patients with COVID-19: A systematic review

Dayane Caroliny Pereira Justino1, David Franciole Oliveira Silva1, Ketyllem Tayanne da Silva Costa2

  • 1Department of Public Health, Federal University of Rio Grande do Norte, Brazil.

Medicine
|October 5, 2022
PubMed

Insights

This systematic review found that a significant percentage of patients who died from coronavirus disease (COVID-19) had pre-existing chronic non-transmissible diseases. Hypertension and diabetes were the most common comorbidities observed in deceased COVID-19 patients.

Area of Science:

  • Medical Research
  • Epidemiology
  • Public Health

Background:

  • The emergence of coronavirus disease (COVID-19) in December 2019 necessitated understanding its pathogenesis.
  • Key factors influencing COVID-19 progression, particularly in relation to chronic conditions, remained unclear.

Purpose of the Study:

  • To systematically review existing literature on the association between COVID-19 infection and chronic non-transmissible diseases in patients who died from the disease.

Main Methods:

  • A systematic literature review was conducted, analyzing observational studies published from December 2019 to September 2020.
  • The review protocol was registered with PROSPERO (CRD42020176249).

Main Results:

  • Analysis of 31 studies included 421,872 COVID-19 patients, with 45,399 (10.8%) fatalities.
  • Hypertension, diabetes mellitus, and respiratory diseases were the most prevalent comorbidities among all patients.
  • The overall cure/recovery rate was 89.2% (376,473 patients).

Conclusions:

  • A high prevalence of comorbidities was observed in COVID-19 patients.
  • Comorbidities were particularly pronounced in patients who succumbed to COVID-19.
Abstract

More Related Videos

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.6K
Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

2.8K

Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
460
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
369
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
35
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.9K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
35
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
25